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The Current State-of-the Art of LRRK2-Based Biomarker Assay Development in Parkinson’s Disease
Evidence is mounting that LRRK2 function, particularly its kinase activity, is elevated in multiple forms of Parkinson’s disease, both idiopathic as well as familial forms linked to mutations in the LRRK2 gene. However, sensitive quantitative markers of LRRK2 activation in clinical samples remain at...
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| Wydane w: | Front Neurosci |
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| Główni autorzy: | , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Frontiers Media S.A.
2020
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7461933/ https://ncbi.nlm.nih.gov/pubmed/33013290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2020.00865 |
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