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GTP binding regulates cellular localization of Parkinson's disease-associated LRRK2
Mutations in leucine-rich repeat kinase 2 (LRRK2) comprise the most common cause of familial Parkinson's disease (PD), and sequence variants modify risk for sporadic PD. Previous studies indicate that LRRK2 interacts with microtubules (MTs) and alters MT-mediated vesicular transport processes....
Shranjeno v:
| izdano v: | Hum Mol Genet |
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| Main Authors: | , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2017
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5886193/ https://ncbi.nlm.nih.gov/pubmed/28453723 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddx161 |
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