LRRK2 Phosphorylation, More Than an Epiphenomenon

Mutations in the Leucine Rich Repeat Kinase 2 (LRRK2) gene are linked to autosomal dominant Parkinson's disease (PD), and genetic variations at the LRRK2 locus are associated with an increased risk for sporadic PD. This gene encodes a kinase that is physiologically multiphosphorylated, includin...

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Detalhes bibliográficos
Publicado no:Front Neurosci
Main Authors: Marchand, Antoine, Drouyer, Matthieu, Sarchione, Alessia, Chartier-Harlin, Marie-Christine, Taymans, Jean-Marc
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7308437/
https://ncbi.nlm.nih.gov/pubmed/32612495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2020.00527
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