Histone Acetyltransferase MOF Orchestrates Outcomes at the Crossroad of Oncogenesis, DNA Damage Response, Proliferation, and Stem Cell Development

The DNA and protein complex known as chromatin is subject to posttranslational modifications (PTMs) that regulate cellular functions such that PTM dysregulation can lead to disease, including cancer. One critical PTM is acetylation/deacetylation, which is being investigated as a means to develop tar...

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Vydáno v:Mol Cell Biol
Hlavní autoři: Singh, Mayank, Bacolla, Albino, Chaudhary, Shilpi, Hunt, Clayton R., Pandita, Shruti, Chauhan, Ravi, Gupta, Ashna, Tainer, John A., Pandita, Tej K.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7459263/
https://ncbi.nlm.nih.gov/pubmed/32661120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00232-20
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