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Histone acetyltransferase activity of MOF is required for adult but not early fetal hematopoiesis in mice

K(lysine) acetyltransferase 8 (KAT8, also known as MOF) mediates the acetylation of histone H4 at lysine 16 (H4K16ac) and is crucial for murine embryogenesis. Lysine acetyltransferases have been shown to regulate various stages of normal hematopoiesis. However, the function of MOF in hematopoietic s...

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Detaylı Bibliyografya
Yayımlandı:Blood
Asıl Yazarlar: Valerio, Daria G., Xu, Haiming, Eisold, Meghan E., Woolthuis, Carolien M., Pandita, Tej K., Armstrong, Scott A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Hematology 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216264/
https://ncbi.nlm.nih.gov/pubmed/27827827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-05-714568
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