Histone Acetyltransferase MOF Orchestrates Outcomes at the Crossroad of Oncogenesis, DNA Damage Response, Proliferation, and Stem Cell Development

The DNA and protein complex known as chromatin is subject to posttranslational modifications (PTMs) that regulate cellular functions such that PTM dysregulation can lead to disease, including cancer. One critical PTM is acetylation/deacetylation, which is being investigated as a means to develop tar...

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Bibliografske podrobnosti
izdano v:Mol Cell Biol
Main Authors: Singh, Mayank, Bacolla, Albino, Chaudhary, Shilpi, Hunt, Clayton R., Pandita, Shruti, Chauhan, Ravi, Gupta, Ashna, Tainer, John A., Pandita, Tej K.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2020
Teme:
Minireview
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7459263/
https://ncbi.nlm.nih.gov/pubmed/32661120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00232-20
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