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MOF Suppresses Replication Stress and Contributes to Resolution of Stalled Replication Forks

The human MOF (hMOF) protein belongs to the MYST family of histone acetyltransferases and plays a critical role in transcription and the DNA damage response. MOF is essential for cell proliferation; however, its role during replication and replicative stress is unknown. Here we demonstrate that cell...

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Veröffentlicht in:Mol Cell Biol
Hauptverfasser: Singh, Dharmendra Kumar, Pandita, Raj K., Singh, Mayank, Chakraborty, Sharmistha, Hambarde, Shashank, Ramnarain, Deepti, Charaka, Vijaya, Ahmed, Kazi Mokim, Hunt, Clayton R., Pandita, Tej K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5829482/
https://ncbi.nlm.nih.gov/pubmed/29298824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00484-17
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