The Mammalian Ortholog of Drosophila MOF That Acetylates Histone H4 Lysine 16 Is Essential for Embryogenesis and Oncogenesis

The mammalian ortholog of the Drosophila MOF (males absent on the first) gene product is a histone H4 lysine 16-specific acetyltransferase. Recent studies have shown that depletion of human MOF (hMOF) in human cell lines leads to genomic instability, spontaneous chromosomal aberrations, cell cycle d...

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Main Authors: Gupta, Arun, Guerin-Peyrou, T. Geraldine, Sharma, Girdhar G., Park, Changwon, Agarwal, Manjula, Ganju, Ramesh K., Pandita, Shruti, Choi, Kyunghee, Sukumar, Saraswati, Pandita, Raj K., Ludwig, Thomas, Pandita, Tej K.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2008
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Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2223300/
https://ncbi.nlm.nih.gov/pubmed/17967868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01045-07
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