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Histone acetyltransferase activity of MOF is required for adult but not early fetal hematopoiesis in mice
K(lysine) acetyltransferase 8 (KAT8, also known as MOF) mediates the acetylation of histone H4 at lysine 16 (H4K16ac) and is crucial for murine embryogenesis. Lysine acetyltransferases have been shown to regulate various stages of normal hematopoiesis. However, the function of MOF in hematopoietic s...
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| Publicat a: | Blood |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society of Hematology
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5216264/ https://ncbi.nlm.nih.gov/pubmed/27827827 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-05-714568 |
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