Dengue virus NS2B protein targets cGAS for degradation and prevents mitochondrial DNA sensing during infection

During the last few decades, the global incidence of dengue virus (DENV) has increased dramatically, and it is now endemic in more than 100 countries. To establish a productive infection in humans, DENV uses different strategies to inhibit or avoid the host innate immune system. Several DENV protein...

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Опубликовано в: :Nat Microbiol
Главные авторы: Aguirre, Sebastian, Luthra, Priya, Sanchez-Aparicio, Maria T., Maestre, Ana M., Patel, Jenish, Lamothe, Francise, Fredericks, Anthony C., Tripathi, Shashank, Zhu, Tongtong, Pintado-Silva, Jessica, Webb, Laurence G., Bernal-Rubio, Dabeiba, Solovyov, Alexander, Greenbaum, Benjamin, Simon, Viviana, Basler, Christopher F., Mulder, Lubbertus C. F., García-Sastre, Adolfo, Fernandez-Sesma, Ana
Формат: Artigo
Язык:Inglês
Опубликовано: 2017
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7457382/
https://ncbi.nlm.nih.gov/pubmed/28346446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmicrobiol.2017.37
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