Dengue Virus Co-opts UBR4 to Degrade STAT2 and Antagonize Type I Interferon Signaling

An estimated 50 million dengue virus (DENV) infections occur annually and more than forty percent of the human population is currently at risk of developing dengue fever (DF) or dengue hemorrhagic fever (DHF). Despite the prevalence and potential severity of DF and DHF, there are no approved vaccine...

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Main Authors: Morrison, Juliet, Laurent-Rolle, Maudry, Maestre, Ana M., Rajsbaum, Ricardo, Pisanelli, Giuseppe, Simon, Viviana, Mulder, Lubbertus C. F., Fernandez-Sesma, Ana, García-Sastre, Adolfo
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610674/
https://ncbi.nlm.nih.gov/pubmed/23555265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003265
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