Dengue Virus Co-opts UBR4 to Degrade STAT2 and Antagonize Type I Interferon Signaling

An estimated 50 million dengue virus (DENV) infections occur annually and more than forty percent of the human population is currently at risk of developing dengue fever (DF) or dengue hemorrhagic fever (DHF). Despite the prevalence and potential severity of DF and DHF, there are no approved vaccine...

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Detalhes bibliográficos
Main Authors: Morrison, Juliet, Laurent-Rolle, Maudry, Maestre, Ana M., Rajsbaum, Ricardo, Pisanelli, Giuseppe, Simon, Viviana, Mulder, Lubbertus C. F., Fernandez-Sesma, Ana, García-Sastre, Adolfo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610674/
https://ncbi.nlm.nih.gov/pubmed/23555265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003265
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