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NS5 of Dengue Virus Mediates STAT2 Binding and Degradation

The mammalian interferon (IFN) signaling pathway is a primary component of the innate antiviral response. As such, viral pathogens have devised multiple mechanisms to antagonize this pathway and thus facilitate infection. Dengue virus (DENV) encodes several proteins (NS2a, NS4a, and NS4b) that have...

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Detalhes bibliográficos
Main Authors: Ashour, Joseph, Laurent-Rolle, Maudry, Shi, Pei-Yong, García-Sastre, Adolfo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2681973/
https://ncbi.nlm.nih.gov/pubmed/19279106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02188-08
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