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NS5 of Dengue Virus Mediates STAT2 Binding and Degradation
The mammalian interferon (IFN) signaling pathway is a primary component of the innate antiviral response. As such, viral pathogens have devised multiple mechanisms to antagonize this pathway and thus facilitate infection. Dengue virus (DENV) encodes several proteins (NS2a, NS4a, and NS4b) that have...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2681973/ https://ncbi.nlm.nih.gov/pubmed/19279106 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02188-08 |
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