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NS5 of Dengue Virus Mediates STAT2 Binding and Degradation

The mammalian interferon (IFN) signaling pathway is a primary component of the innate antiviral response. As such, viral pathogens have devised multiple mechanisms to antagonize this pathway and thus facilitate infection. Dengue virus (DENV) encodes several proteins (NS2a, NS4a, and NS4b) that have...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Ashour, Joseph, Laurent-Rolle, Maudry, Shi, Pei-Yong, García-Sastre, Adolfo
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology (ASM) 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2681973/
https://ncbi.nlm.nih.gov/pubmed/19279106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02188-08
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