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Mouse STAT2 Restricts Early Dengue Virus Replication
Dengue virus encodes several interferon antagonists. Among these the NS5 protein binds STAT2, a necessary component of the type-I interferon signaling pathway, and targets it for degradation. We now demonstrate that the ability of dengue NS5 to associate with and degrade STAT2 is species specific. T...
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| Hauptverfasser: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3310429/ https://ncbi.nlm.nih.gov/pubmed/21075352 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2010.10.007 |
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