Chikungunya virus antagonizes cGAS-STING mediated type-I interferon responses by degrading cGAS

Chikungunya virus (CHIKV) is a mosquito-borne alphavirus known to cause epidemics resulting in predominantly symptomatic infections, which in rare cases cause long term debilitating arthritis and arthralgia. Significant progress has been made in understanding the roles of canonical RNA sensing pathw...

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Publicado en:PLoS Pathog
Main Authors: Webb, L. G., Veloz, J., Pintado-Silva, J., Zhu, T., Rangel, M. V., Mutetwa, T., Zhang, L., Bernal-Rubio, D., Figueroa, D., Carrau, L., Fenutria, R., Potla, U., Reid, St. P., Yount, J. S., Stapleford, K. A., Aguirre, S., Fernandez-Sesma, A.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2020
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7591055/
https://ncbi.nlm.nih.gov/pubmed/33057424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008999
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