Chikungunya virus antagonizes cGAS-STING mediated type-I interferon responses by degrading cGAS

Chikungunya virus (CHIKV) is a mosquito-borne alphavirus known to cause epidemics resulting in predominantly symptomatic infections, which in rare cases cause long term debilitating arthritis and arthralgia. Significant progress has been made in understanding the roles of canonical RNA sensing pathw...

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Bibliografiska uppgifter
I publikationen:PLoS Pathog
Huvudupphovsmän: Webb, L. G., Veloz, J., Pintado-Silva, J., Zhu, T., Rangel, M. V., Mutetwa, T., Zhang, L., Bernal-Rubio, D., Figueroa, D., Carrau, L., Fenutria, R., Potla, U., Reid, St. P., Yount, J. S., Stapleford, K. A., Aguirre, S., Fernandez-Sesma, A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2020
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7591055/
https://ncbi.nlm.nih.gov/pubmed/33057424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008999
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