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Chikungunya virus antagonizes cGAS-STING mediated type-I interferon responses by degrading cGAS

Chikungunya virus (CHIKV) is a mosquito-borne alphavirus known to cause epidemics resulting in predominantly symptomatic infections, which in rare cases cause long term debilitating arthritis and arthralgia. Significant progress has been made in understanding the roles of canonical RNA sensing pathw...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS Pathog
Prif Awduron: Webb, L. G., Veloz, J., Pintado-Silva, J., Zhu, T., Rangel, M. V., Mutetwa, T., Zhang, L., Bernal-Rubio, D., Figueroa, D., Carrau, L., Fenutria, R., Potla, U., Reid, St. P., Yount, J. S., Stapleford, K. A., Aguirre, S., Fernandez-Sesma, A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7591055/
https://ncbi.nlm.nih.gov/pubmed/33057424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008999
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