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The Complexity of the cGAS-STING Pathway in CNS Pathologies

Neuroinflammation driven by type-I interferons in the CNS is well established to exacerbate the progression of many CNS pathologies both acute and chronic. The role of adaptor protein Stimulator of Interferon Genes (STING) is increasingly appreciated to instigate type-I IFN-mediated neuroinflammatio...

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Detalhes bibliográficos
Publicado no:Front Neurosci
Main Authors: Fryer, Amelia L., Abdullah, Amar, Taylor, Juliet M., Crack, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7900568/
https://ncbi.nlm.nih.gov/pubmed/33633536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2021.621501
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