DENV Inhibits Type I IFN Production in Infected Cells by Cleaving Human STING

Dengue virus (DENV) is a pathogen with a high impact on human health. It replicates in a wide range of cells involved in the immune response. To efficiently infect humans, DENV must evade or inhibit fundamental elements of the innate immune system, namely the type I interferon response. DENV circumv...

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Detalhes bibliográficos
Main Authors: Aguirre, Sebastian, Maestre, Ana M., Pagni, Sarah, Patel, Jenish R., Savage, Timothy, Gutman, Delia, Maringer, Kevin, Bernal-Rubio, Dabeiba, Shabman, Reed S., Simon, Viviana, Rodriguez-Madoz, Juan R., Mulder, Lubbertus C. F., Barber, Glen N., Fernandez-Sesma, Ana
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464218/
https://ncbi.nlm.nih.gov/pubmed/23055924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002934
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