Reduced left atrial cardiomyocyte PITX2 and elevated circulating BMP10 predict atrial fibrillation after ablation

BACKGROUND: Genomic and experimental studies suggest a role for PITX2 in atrial fibrillation (AF). To assess if this association is relevant for recurrent AF in patients, we tested whether left atrial PITX2 affects recurrent AF after AF ablation. METHODS: mRNA concentrations of PITX2 and its cardiac...

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Bibliographic Details
Published in:JCI Insight
Main Authors: Reyat, Jasmeet S., Chua, Winnie, Cardoso, Victor R., Witten, Anika, Kastner, Peter M., Kabir, S. Nashitha, Sinner, Moritz F., Wesselink, Robin, Holmes, Andrew P., Pavlovic, Davor, Stoll, Monika, Kääb, Stefan, Gkoutos, Georgios V., de Groot, Joris R., Kirchhof, Paulus, Fabritz, Larissa
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2020
Subjects:
Clinical Medicine
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7455124/
https://ncbi.nlm.nih.gov/pubmed/32814717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.139179
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