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PITX2 Modulates Atrial Membrane Potential and the Antiarrhythmic Effects of Sodium-Channel Blockers

BACKGROUND: Antiarrhythmic drugs are widely used to treat patients with atrial fibrillation (AF), but the mechanisms conveying their variable effectiveness are not known. Recent data suggested that paired like homeodomain-2 transcription factor (PITX2) might play an important role in regulating gene...

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Dettagli Bibliografici
Pubblicato in:J Am Coll Cardiol
Autori principali: Syeda, Fahima, Holmes, Andrew P., Yu, Ting Y., Tull, Samantha, Kuhlmann, Stefan Michael, Pavlovic, Davor, Betney, Daniel, Riley, Genna, Kucera, Jan P., Jousset, Florian, de Groot, Joris R., Rohr, Stephan, Brown, Nigel A., Fabritz, Larissa, Kirchhof, Paulus
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier Biomedical 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5075046/
https://ncbi.nlm.nih.gov/pubmed/27765191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2016.07.766
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