PITX2 Modulates Atrial Membrane Potential and the Antiarrhythmic Effects of Sodium-Channel Blockers

BACKGROUND: Antiarrhythmic drugs are widely used to treat patients with atrial fibrillation (AF), but the mechanisms conveying their variable effectiveness are not known. Recent data suggested that paired like homeodomain-2 transcription factor (PITX2) might play an important role in regulating gene...

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Detalles Bibliográficos
Publicado en:J Am Coll Cardiol
Main Authors: Syeda, Fahima, Holmes, Andrew P., Yu, Ting Y., Tull, Samantha, Kuhlmann, Stefan Michael, Pavlovic, Davor, Betney, Daniel, Riley, Genna, Kucera, Jan P., Jousset, Florian, de Groot, Joris R., Rohr, Stephan, Brown, Nigel A., Fabritz, Larissa, Kirchhof, Paulus
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier Biomedical 2016
Assuntos:
Original Investigation
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5075046/
https://ncbi.nlm.nih.gov/pubmed/27765191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2016.07.766
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