A Regional Reduction in I(to) and I(KACh) in the Murine Posterior Left Atrial Myocardium Is Associated with Action Potential Prolongation and Increased Ectopic Activity

BACKGROUND: The left atrial posterior wall (LAPW) is potentially an important area for the development and maintenance of atrial fibrillation. We assessed whether there are regional electrical differences throughout the murine left atrial myocardium that could underlie regional differences in arrhyt...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Holmes, Andrew P., Yu, Ting Y., Tull, Samantha, Syeda, Fahima, Kuhlmann, Stefan M., O’Brien, Sian-Marie, Patel, Pushpa, Brain, Keith L., Pavlovic, Davor, Brown, Nigel A., Fabritz, Larissa, Kirchhof, Paulus
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4858288/
https://ncbi.nlm.nih.gov/pubmed/27149380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0154077
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