Reduced left atrial cardiomyocyte PITX2 and elevated circulating BMP10 predict atrial fibrillation after ablation

BACKGROUND: Genomic and experimental studies suggest a role for PITX2 in atrial fibrillation (AF). To assess if this association is relevant for recurrent AF in patients, we tested whether left atrial PITX2 affects recurrent AF after AF ablation. METHODS: mRNA concentrations of PITX2 and its cardiac...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Reyat, Jasmeet S., Chua, Winnie, Cardoso, Victor R., Witten, Anika, Kastner, Peter M., Kabir, S. Nashitha, Sinner, Moritz F., Wesselink, Robin, Holmes, Andrew P., Pavlovic, Davor, Stoll, Monika, Kääb, Stefan, Gkoutos, Georgios V., de Groot, Joris R., Kirchhof, Paulus, Fabritz, Larissa
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2020
Assuntos:
Clinical Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7455124/
https://ncbi.nlm.nih.gov/pubmed/32814717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.139179
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