Reduced left atrial cardiomyocyte PITX2 and elevated circulating BMP10 predict atrial fibrillation after ablation

BACKGROUND: Genomic and experimental studies suggest a role for PITX2 in atrial fibrillation (AF). To assess if this association is relevant for recurrent AF in patients, we tested whether left atrial PITX2 affects recurrent AF after AF ablation. METHODS: mRNA concentrations of PITX2 and its cardiac...

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書誌詳細
出版年:JCI Insight
主要な著者: Reyat, Jasmeet S., Chua, Winnie, Cardoso, Victor R., Witten, Anika, Kastner, Peter M., Kabir, S. Nashitha, Sinner, Moritz F., Wesselink, Robin, Holmes, Andrew P., Pavlovic, Davor, Stoll, Monika, Kääb, Stefan, Gkoutos, Georgios V., de Groot, Joris R., Kirchhof, Paulus, Fabritz, Larissa
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 2020
主題:
Clinical Medicine
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7455124/
https://ncbi.nlm.nih.gov/pubmed/32814717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.139179
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