Atrial resting membrane potential confers sodium current sensitivity to propafenone, flecainide and dronedarone

BACKGROUND: Although atrial fibrillation ablation is increasingly used for rhythm control therapy, antiarrhythmic drugs (AADs) are commonly used, either alone or in combination with ablation. The effectiveness of AADs is highly variable. Previous work from our group suggests that alterations in atri...

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Dettagli Bibliografici
Pubblicato in:Heart Rhythm
Autori principali: Holmes, Andrew P., Saxena, Priyanka, Kabir, S. Nashitha, O’Shea, Christopher, Kuhlmann, Stefan M., Gupta, Suranjana, Fobian, Dannie, Apicella, Clara, O’Reilly, Molly, Syeda, Fahima, Reyat, Jasmeet S., Smith, Godfrey L., Workman, Antony J., Pavlovic, Davor, Fabritz, Larissa, Kirchhof, Paulus
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2021
Soggetti:
Experimental
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8259123/
https://ncbi.nlm.nih.gov/pubmed/33737232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.hrthm.2021.03.016
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