Atrial resting membrane potential confers sodium current sensitivity to propafenone, flecainide and dronedarone

BACKGROUND: Although atrial fibrillation ablation is increasingly used for rhythm control therapy, antiarrhythmic drugs (AADs) are commonly used, either alone or in combination with ablation. The effectiveness of AADs is highly variable. Previous work from our group suggests that alterations in atri...

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Bibliografiske detaljer
Udgivet i:Heart Rhythm
Main Authors: Holmes, Andrew P., Saxena, Priyanka, Kabir, S. Nashitha, O’Shea, Christopher, Kuhlmann, Stefan M., Gupta, Suranjana, Fobian, Dannie, Apicella, Clara, O’Reilly, Molly, Syeda, Fahima, Reyat, Jasmeet S., Smith, Godfrey L., Workman, Antony J., Pavlovic, Davor, Fabritz, Larissa, Kirchhof, Paulus
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2021
Fag:
Experimental
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8259123/
https://ncbi.nlm.nih.gov/pubmed/33737232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.hrthm.2021.03.016
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