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Diagnostic Investigation of Lesions Associated with Succinate Dehydrogenase Defects
The mitochondrial enzyme succinate dehydrogenase (SDH) acts as a tumor suppressor. Biallelic inactivation of one of the genes encoding for SDH subunits (collectively named SDHx) leads to complete loss of the protein function and the development of diverse group of tumors. Pheochromocytomas-paragangl...
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| Published in: | Horm Metab Res |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2018
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7444674/ https://ncbi.nlm.nih.gov/pubmed/29618137 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/a-0586-3710 |
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