Mediastinal paragangliomas: association with mutations in the succinate dehydrogenase genes and aggressive behavior

Extra-adrenal pheochromocytomas, otherwise known as paragangliomas (PGLs), account for about 20% of catecholamine-producing tumors. Catecholamine excess and mutations in the genes encoding succinate dehydrogenase subunits (SDHx) are frequently found in patients with PGLs. Only 2% of PGLs are found i...

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Bibliographic Details
Published in:Endocr Relat Cancer
Main Authors: Ghayee, Hans K, Havekes, Bas, Corssmit, Eleonora P M, Eisenhofer, Graeme, Hammes, Stephen R, Ahmad, Zahid, Tessnow, Alexander, Lazúrová, Ivica, Adams, Karen T, Fojo, Antonio T, Pacak, Karel, Auchus, Richard J
Format: Artigo
Language:Inglês
Published: 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4718401/
https://ncbi.nlm.nih.gov/pubmed/19075037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1677/ERC-08-0214
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