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Diagnostic Investigation of Lesions Associated with Succinate Dehydrogenase Defects

The mitochondrial enzyme succinate dehydrogenase (SDH) acts as a tumor suppressor. Biallelic inactivation of one of the genes encoding for SDH subunits (collectively named SDHx) leads to complete loss of the protein function and the development of diverse group of tumors. Pheochromocytomas-paragangl...

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Publicat a:Horm Metab Res
Autors principals: Taïeb, David, Timmers, Henri, Pacak, Karel
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7444674/
https://ncbi.nlm.nih.gov/pubmed/29618137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/a-0586-3710
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