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Diagnostic Investigation of Lesions Associated with Succinate Dehydrogenase Defects
The mitochondrial enzyme succinate dehydrogenase (SDH) acts as a tumor suppressor. Biallelic inactivation of one of the genes encoding for SDH subunits (collectively named SDHx) leads to complete loss of the protein function and the development of diverse group of tumors. Pheochromocytomas-paragangl...
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| Publié dans: | Horm Metab Res |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7444674/ https://ncbi.nlm.nih.gov/pubmed/29618137 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/a-0586-3710 |
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