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Counseling patients with succinate dehydrogenase subunit defects: genetics, preventive guidelines, and dealing with uncertainty

The discovery that mutations in the succinate dehydrogenase (SDH) complex subunit (SDHA, B/C/D/AF2) genes predispose patients to the development of tumors has led to the identification of a large population of patients and relatives at risk for developing malignancies. The most frequent conditions a...

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Detalhes bibliográficos
Publicado no:J Pediatr Endocrinol Metab
Main Authors: Raygada, Margarita, King, Kathryn S., Adams, Karen T., Stratakis, Constantine A., Pacak, Karel
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4718145/
https://ncbi.nlm.nih.gov/pubmed/24854530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/jpem-2013-0369
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