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Diagnostic Investigation of Lesions Associated with Succinate Dehydrogenase Defects
The mitochondrial enzyme succinate dehydrogenase (SDH) acts as a tumor suppressor. Biallelic inactivation of one of the genes encoding for SDH subunits (collectively named SDHx) leads to complete loss of the protein function and the development of diverse group of tumors. Pheochromocytomas-paragangl...
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| Veröffentlicht in: | Horm Metab Res |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7444674/ https://ncbi.nlm.nih.gov/pubmed/29618137 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/a-0586-3710 |
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