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Robust Sequence Determinants of α-Synuclein Toxicity in Yeast Implicate Membrane Binding
Protein conformations are shaped by cellular environments, but how environmental changes alter the conformational landscapes of specific proteins in vivo remains largely uncharacterized, in part due to the challenge of probing protein structures in living cells. Here, we use deep mutational scanning...
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| Publicat a: | ACS Chem Biol |
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| Autors principals: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7442712/ https://ncbi.nlm.nih.gov/pubmed/32786289 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.0c00339 |
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