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Triggered Release Enhances the Cytotoxicity of Stable Colloidal Drug Aggregates
Chemotherapeutics that self-assemble into colloids have limited efficacy above their critical aggregation concentration due to their inability to penetrate intact plasma membranes. Even when colloid uptake is promoted, issues with colloid escape from the endolysosomal pathway persist. By stabilizing...
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| Publicado no: | ACS Chem Biol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7136197/ https://ncbi.nlm.nih.gov/pubmed/31243955 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.9b00247 |
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