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Triggered Release Enhances the Cytotoxicity of Stable Colloidal Drug Aggregates
Chemotherapeutics that self-assemble into colloids have limited efficacy above their critical aggregation concentration due to their inability to penetrate intact plasma membranes. Even when colloid uptake is promoted, issues with colloid escape from the endolysosomal pathway persist. By stabilizing...
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| 出版年: | ACS Chem Biol |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7136197/ https://ncbi.nlm.nih.gov/pubmed/31243955 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.9b00247 |
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