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Colloidal aggregation: from screening nuisance to formulation nuance

It is well known that small molecule colloidal aggregation is a leading cause of false positives in early drug discovery. Colloid-formers are diverse and well represented among corporate and academic screening decks, and even among approved drugs. Less appreciated is how colloid formation by drug-li...

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Publicado en:Nano Today
Main Authors: Ganesh, Ahil N., Donders, Eric N., Shoichet, Brian K., Shoichet, Molly S.
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6150470/
https://ncbi.nlm.nih.gov/pubmed/30250495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nantod.2018.02.011
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