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Internal Structure and Preferential Protein Binding of Colloidal Aggregates
Colloidal aggregates of small molecules are the most common artifact in early drug discovery, sequestering and inhibiting target proteins without specificity. Understanding their structure and mechanism has been crucial to developing tools to control for, and occasionally even exploit, these particl...
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| Publicado no: | ACS Chem Biol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5491102/ https://ncbi.nlm.nih.gov/pubmed/27983786 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.6b00791 |
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