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Internal Structure and Preferential Protein Binding of Colloidal Aggregates
Colloidal aggregates of small molecules are the most common artifact in early drug discovery, sequestering and inhibiting target proteins without specificity. Understanding their structure and mechanism has been crucial to developing tools to control for, and occasionally even exploit, these particl...
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| Wydane w: | ACS Chem Biol |
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| Główni autorzy: | , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2016
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5491102/ https://ncbi.nlm.nih.gov/pubmed/27983786 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.6b00791 |
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