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A DNA damage signal activates and derepresses exon inclusion in Drosophila TAF1 alternative splicing

Signal-dependent alternative splicing is important for regulating gene expression in eukaryotes, yet our understanding of how signals impact splicing mechanisms is limited. A model to address this issue is alternative splicing of Drosophila TAF1 pre-mRNA in response to camptothecin (CPT)-induced DNA...

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Detalhes bibliográficos
Main Authors: Marengo, Matthew S., Wassarman, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2491473/
https://ncbi.nlm.nih.gov/pubmed/18596254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1048808
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