Genetic deletion of microRNA-22 blunts the inflammatory transcriptional response to status epilepticus and exacerbates epilepsy in mice

MicroRNAs perform important roles in the post-transcriptional regulation of gene expression. Sequencing as well as functional studies using antisense oligonucleotides indicate important roles for microRNAs during the development of epilepsy through targeting transcripts involved in neuronal structur...

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Udgivet i:Mol Brain
Main Authors: Almeida Silva, Luiz F., Reschke, Cristina R., Nguyen, Ngoc T., Langa, Elena, Sanz-Rodriguez, Amaya, Gerbatin, Rogerio R., Temp, Fernanda R., de Freitas, Mayara L., Conroy, Ronan M., Brennan, Gary P., Engel, Tobias, Henshall, David C.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7441563/
https://ncbi.nlm.nih.gov/pubmed/32825833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-020-00653-x
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