Deletion of the BH3-only protein Noxa alters electrographic seizures but does not protect against hippocampal damage after status epilepticus in mice

Several members of the Bcl-2 gene family are dysregulated in human temporal lobe epilepsy and animal studies show that genetic deletion of some of these proteins influence electrographic seizure responses to chemoconvulsants and associated brain damage. The BH3-only proteins form a subgroup comprisi...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Ichikawa, Naoki, Alves, Mariana, Pfeiffer, Shona, Langa, Elena, Hernández-Santana, Yasmina E, Suzuki, Hidenori, Prehn, Jochen HM, Engel, Tobias, Henshall, David C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5457684/
https://ncbi.nlm.nih.gov/pubmed/28079889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.301
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