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Genetic deletion of microRNA-22 blunts the inflammatory transcriptional response to status epilepticus and exacerbates epilepsy in mice

MicroRNAs perform important roles in the post-transcriptional regulation of gene expression. Sequencing as well as functional studies using antisense oligonucleotides indicate important roles for microRNAs during the development of epilepsy through targeting transcripts involved in neuronal structur...

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Detalhes bibliográficos
Publicado no:Mol Brain
Main Authors: Almeida Silva, Luiz F., Reschke, Cristina R., Nguyen, Ngoc T., Langa, Elena, Sanz-Rodriguez, Amaya, Gerbatin, Rogerio R., Temp, Fernanda R., de Freitas, Mayara L., Conroy, Ronan M., Brennan, Gary P., Engel, Tobias, Henshall, David C.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7441563/
https://ncbi.nlm.nih.gov/pubmed/32825833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-020-00653-x
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