GD2-directed CAR-T cells in combination with HGF-targeted neutralizing antibody (AMG102) prevent primary tumor growth and metastasis in Ewing Sarcoma

Ewing sarcoma (EWS) is the second most common and aggressive type of metastatic bone tumor in adolescents and young adults. There is unmet medical need to develop and test novel pharmacological targets and novel therapies to treat EWS. Here, we found that EWS expresses high levels of a p53 isoform,...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Int J Cancer
Main Authors: Charan, Manish, Dravid, Piyush, Cam, Maren, Audino, Anthony, Gross, Amy C., Arnold, Michael A., Roberts, Ryan D., Cripe, Timothy P., Pertsemlidis, Alexander, Houghton, Peter J., Cam, Hakan
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7440656/
https://ncbi.nlm.nih.gov/pubmed/31621900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.32743
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker