Tumor secreted ANGPTL2 facilitates recruitment of neutrophils to the lung to promote lung pre-metastatic niche formation and targeting ANGPTL2 signaling affects metastatic disease

The pre-metastatic niche (PMN) represents an abnormal microenvironment devoid of cancer cells, but favoring tumor growth. Little is known about the mechanisms that generate the PMN or their effects on host cells within metastasis-prone organs. Here, we investigated by using spontaneous metastatic mo...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Charan, Manish, Dravid, Piyush, Cam, Maren, Setty, Bhuvana, Roberts, Ryan D., Houghton, Peter J., Cam, Hakan
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2020
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7007290/
https://ncbi.nlm.nih.gov/pubmed/32082485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27433
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