Tumor secreted ANGPTL2 facilitates recruitment of neutrophils to the lung to promote lung pre-metastatic niche formation and targeting ANGPTL2 signaling affects metastatic disease

The pre-metastatic niche (PMN) represents an abnormal microenvironment devoid of cancer cells, but favoring tumor growth. Little is known about the mechanisms that generate the PMN or their effects on host cells within metastasis-prone organs. Here, we investigated by using spontaneous metastatic mo...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Charan, Manish, Dravid, Piyush, Cam, Maren, Setty, Bhuvana, Roberts, Ryan D., Houghton, Peter J., Cam, Hakan
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2020
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7007290/
https://ncbi.nlm.nih.gov/pubmed/32082485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27433
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