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Red blood cell adhesion to ICAM-1 is mediated by fibrinogen and is associated with right-to-left shunts in sickle cell disease

Sickle cell disease (SCD), which afflicts 100 000 Americans, as well as millions worldwide, is associated with anemia, lifelong morbidity, and early mortality. Abnormal adhesion of sickle red blood cells (RBCs) to activated vascular endothelium may contribute acutely to the initiation of painful vas...

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書誌詳細
出版年:Blood Adv
主要な著者: Kucukal, Erdem, Man, Yuncheng, Quinn, Erina, Tewari, Neil, An, Ran, Ilich, Anton, Key, Nigel S., Little, Jane A., Gurkan, Umut A.
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Hematology 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7422136/
https://ncbi.nlm.nih.gov/pubmed/32777069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020001656
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