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Standardized microfluidic assessment of red blood cell mediated microcapillary occlusion: Association with clinical phenotype and hydroxyurea responsiveness in sickle cell disease
OBJECTIVES: We present a standardized in vitro microfluidic assay and Occlusion Index (OI) for the assessment of red blood cell (RBC)-mediated microcapillary occlusion and its clinical associations in sickle cell disease (SCD). METHODS: RBC-mediated microcapillary occlusion represented by OI and its...
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| Publicado no: | Microcirculation |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7920910/ https://ncbi.nlm.nih.gov/pubmed/33025653 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/micc.12662 |
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