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Loss of the Essential Autophagy Regulators FIP200 or Atg5 Leads to Distinct Effects on Focal Adhesion Composition and Organization

Autophagy is an essential catabolic intracellular pathway that maintains homeostasis by degrading long-lived proteins, damaged organelles, and provides an energy source during nutrient starvation. It is now understood that autophagy has discrete functions as a selective lysosomal degradation pathway...

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Detalles Bibliográficos
Publicado en:Front Cell Dev Biol
Main Authors: Assar, Emelia A., Tumbarello, David A.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7417463/
https://ncbi.nlm.nih.gov/pubmed/32850845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00733
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