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Loss of the Essential Autophagy Regulators FIP200 or Atg5 Leads to Distinct Effects on Focal Adhesion Composition and Organization

Autophagy is an essential catabolic intracellular pathway that maintains homeostasis by degrading long-lived proteins, damaged organelles, and provides an energy source during nutrient starvation. It is now understood that autophagy has discrete functions as a selective lysosomal degradation pathway...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Assar, Emelia A., Tumbarello, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7417463/
https://ncbi.nlm.nih.gov/pubmed/32850845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00733
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