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Regulation of Focal Adhesion Kinase by a Novel Protein Inhibitor FIP200

Focal adhesion kinase (FAK) is a major mediator of integrin signaling pathways. The mechanisms of regulation of FAK activity and its associated cellular functions are not very well understood. Here, we present data suggesting that a novel protein FIP200 functions as an inhibitor for FAK. We show the...

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Autors principals: Abbi, Smita, Ueda, Hiroki, Zheng, Chuanhai, Cooper, Lee Ann, Zhao, Jihe, Christopher, Renee, Guan, Jun-Lin
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC124151/
https://ncbi.nlm.nih.gov/pubmed/12221124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E02-05-0295
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