Llwytho...

Regulation of Focal Adhesion Kinase by Its Amino-Terminal Domain through an Autoinhibitory Interaction

We have investigated a role for the amino-terminal FERM-like domain of the focal adhesion kinase (FAK) as a negative regulator of its own activity and phosphorylation state. Deletion of the first 375 amino acids from the amino terminus of FAK increases its catalytic activity in vitro, its phosphoryl...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Cooper, Lee Ann, Shen, Tang-Long, Guan, Jun-Lin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2003
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC262338/
https://ncbi.nlm.nih.gov/pubmed/14585964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.22.8030-8041.2003
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