Regulation of Focal Adhesion Kinase by Its Amino-Terminal Domain through an Autoinhibitory Interaction
We have investigated a role for the amino-terminal FERM-like domain of the focal adhesion kinase (FAK) as a negative regulator of its own activity and phosphorylation state. Deletion of the first 375 amino acids from the amino terminus of FAK increases its catalytic activity in vitro, its phosphoryl...
שמור ב:
| הוצא לאור ב: | Mol Cell Biol |
|---|---|
| Principais autores: | , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Taylor & Francis
2003
|
| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC262338/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14585964/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.22.8030-8041.2003 |
| תגים: |
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!
|