Delivery of Antisense Oligonucleotides to the Cornea

Antisense oligonucleotides (ASOs) are synthetic nucleic acids that recognize complementary RNA sequences inside cells and modulate gene expression. In this study, we explore the feasibility of ASO delivery to the cornea. We used quantitative polymerase chain reaction to test the efficacy of a benchm...

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Bibliographic Details
Published in:Nucleic Acid Ther
Main Authors: Chau, Viet Q., Hu, Jiaxin, Gong, Xin, Hulleman, John D., Ufret-Vincenty, Rafael L., Rigo, Frank, Prakash, Thahza P., Corey, David R., Mootha, V. Vinod
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc., publishers 2020
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Original Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7415875/
https://ncbi.nlm.nih.gov/pubmed/32202944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/nat.2019.0838
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